Glycomics Conferences | USA | Biochemistry Conferences | Worldwide Events | Europe | Canada | UK | 2016

Theme: To evaluate the entire complement of sugars in an Organism

Biochem Congress 2016

Biochem Congress 2016

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About Conference

ConferenceSeries Ltd welcomes you to attend the International Conference and Glycomics to be held during December 01-02, 2016 in Atlanta, USA. The attending delegates include Editorial Board Members of related supporting journals. This is an excellent opportunity for the delegates from Universities and Institutes to interact with the world class Scientists.

Track 1: Glycoproteomics

Comprehensive characterization of protein glycosylation is critical for understanding the structure and function of glycoproteins. However, due to the complexity and heterogeneity of glycoprotein conformations, current glycoprotein analyses focus mainly on either the de-glycosylated glycosylation site (glycosite)-containing peptides or the released glycans. Here, we describe a chemo enzymatic method called solid phase extraction of N-linkedglycans and glycoside-containing peptides (NGAG) for the comprehensive characterization of glycoproteins that is able to determine glycan heterogeneity for individual glycosides in addition to providing information about the total N-linked glycan, glycoside-containing peptide and glycoprotein content of complex samples

Relevant Conferences

International Conference on Structural Biology, June 23-24, 2016 New Orleans, USA; World Congress on Amino Acids and Proteins, December 08-09, 2016 Baltimore, USA; 6^th International Conference on Bioinformatics, March 29-30, 2016 Valencia, Spain; International Conference on Nucleic Acids, August 04-06, 2016 Seattle, USA; 7^th International Conference on Proteomics, October 24-26, 2016 Rome, Italy; International Conference on Obesity & Chronic Diseases, July 25-27, 2016 Las Vegas USA; International Conference on New Therapeutics for Diabetes and Obesity, April 17-20, 2016 La Jolla, USA; Conference on Plasma Spectrochemistry, January 10-16, 2016 Tucson, USA; Euro Fed Lipid Congress, September 18-21, 2016 Gent, Belgium; Society for Glycobiology, 2016; International Obesity and Adipose Tissue Biology Conference, February 15-19, 2016 Banff, Canada

Track 2: Clinical Glycomics

Glycomics mainly refers in particular to the enzymatic process that attaches glycans to proteins, lipids, or other organic molecules. This enzymatic process produces one of the fundamental biopolymers found in cells (along with DNA, RNA, and proteins). Glycosylation also plays a role in cell-cell adhesion (a mechanism employed by cells of the immune system) via sugar-binding proteins called lectins, which recognize specific carbohydrate moieties.

Nucleic acids, proteins, lipids, and glycans are the four classes of biomolecules that define life. Recent advances in life science research have painted a very different point of view of the importance of these quintessential biomolecules. Even though our knowledge is still limited, glycans are becoming more important to other fields such as vaccines, therapeutics, diagnostics, materials, and energy. This will subsequently speed up the advancement in other fields, such as research on carbohydrate-based vaccines that require access to well-defined carbohydrate structures and tools.

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Track 3: Glycomic Analysis

Glycomic analysis increases the diversity of the proteome to a level unmatched by any other post-translational modification. Glycosidases catalyze the hydrolysis of glycosidic bonds to remove sugars from proteins. These enzymes are critical for glycan processing in the ER and Golgi, and each enzyme shows specificity for removing a particular sugar (e.g., mannosidase). Both membrane proteins and the ECM are highly glycosylated, and O-glycans are essential for proper ECM function and communication between cells and the ECM. Several Glycoepitomics forms of CMD are known to result from dysfunctional O-glycosylation of membrane and ECM proteins; however, one-third of CMDs arise from an unknown genetic etiology.

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Track 4: Glycomic immunotherapies

Nature appears to have taken full advantage of the vast diversity of glycans expressed in organisms by evolving protein modules to recognize discrete glycans that mediate specific physiological or pathological processes. Excluding glycan-specific antibodies, GBPs broadly into two major groups such as lectins and glycosaminoglycan-binding proteins. Most lectins are members of families with defined “carbohydrate-recognition domains” (CRDs) that apparently evolved from shared ancestral genes, often retaining specific features of primary amino acid sequence or three-dimensional structure. Thus, new family members can be identified by searching protein sequence or structural databases.

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Track 5: NGS & Data Analysis Technologies

Growth of the mesh-like peptidoglycan (PG) sacculus located between the bacterial inner and outer membranes (OM) is tightly regulated to ensure cellular integrity, maintain cell shape, and orchestrate division. Cytoskeletal elements direct placement and activity of PG synthases from inside the cell, but precise spatiotemporal control over this process is poorly understood. Glycan catabolism contains metabolic pathway maps for glycans. Some of them contain an alternative representation of glycan biosynthesis or degradation, called the glycan structure map. In mammals, complex N-glycans are involved in different cellular processes including molecular recognition and signaling events.

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Track 6: Developmental Biology

The recent development of new tools and techniques to study and produce structurally defined carbohydrates has spurred renewed interest in the therapeutic applications of glycans. Essentials of glycobiology review focuses on advances within the past decade that are bringing glycan-based treatments back to the forefront of medicine and the technologies that are driving these efforts. These include the use of glycans themselves as therapeutic molecules as well as engineering protein and cell surface glycans to suit clinical applications to that of databases providing glycoenzyme data. Glycan therapeutics offer a rich and promising frontier for developments in the academic, biopharmaceutical, and medical fields.

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Track 7: Microbial & Human Genetics

However, the general development in this field can still be considered as being in its infancy when compared to the genomics and proteomics areas. In terms of bioinformatics in glycobiology, there are several paths of research that are currently in progress. Several algorithms and models have been developed for glycobiology research in the past several years. The development and use of informatics tools and databases for glycobiology and glycomics research has increased considerably in recent years. The development of algorithms and software tools for interpretation of glycans to reliably support the characterization of glycan structures for high-throughput applications is the most immediate demand of the glycomics community.

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Track 8: Neurodegenerative Diseases

Carbohydrates form a diverse group of biomolecules which play active parts in most physiological processes. The field of structural glycobiology concerns the structures of the glycans themselves, the proteins which interact with them and the nature of the interactions between the two. Drug targeting is important for our understanding of human health and disease, and for development of new therapeutic strategies. The experts at the Complex Carbohydrate Research Center have experience and knowledge that make us a world leader in this field, and are creating technologies and tools that are the foundation for the next generation of diagnostics and treatments.

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Track 9: Glycomics Pathway Analysis

Glycomic studies reveal the center of many disorders and diseases sparking the possibility of exploiting them for therapeutic and diagnostic purposes. There are many biochemical pathways and diseases in which glycans are intricately involved. However, times are changing and glycobiologists and immunologists are now collaborating extensively to explore this very fertile area of immunobiology. Numerous carbohydrate-binding proteins, or lectins, have been identified on the surfaces of immune cells. Interactions of lectins with glycans usually require several monosaccharide moieties presented in the correct conformation for high-affinity binding.

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Track 10: Molecular Genetics & Genomics

Molecular Genetics is a field within biology aimed at understanding biological processes and emerging from dynamic interactions of individual components operating at multiple spatiotemporal scales. It is now an established and fundamental interdisciplinary research field. Systems biology studies biological systems by systematically perturbing them (biologically, genetically, or chemically); monitoring the gene, protein, and informational pathway responses; integrating these data; ultimately, formulating mathematical models that describe the structure of the system and predict its response to individual perturbations. Declines in the cost of generating genomic data have made DNA sequencing, RNA-seq, and high-throughput screening an increasingly important part of biomedical research.

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Track 11: Glycomics Diseases:

Innate immunity is the front line of self-defense against infectious non-self in vertebrates and invertebrates. The innate immune system is mediated by germ-line encoding pattern recognition molecules (pathogen sensors) that recognize conserved molecular patterns present in the pathogens but absent in the host. Peptidoglycans (PGN) are essential cell wall components of almost all bacteria, except mycoplasma lacking a cell wall, which provides the host immune system an advantage for detecting invading bacteria. Several families of pattern recognition molecules that detect PGN and PGN-derived compounds have been identified, and the role of PGRP family members in host defense is relatively well-characterized in Drosophila. This review focuses on the role of PGRP family members in the recognition of invading bacteria and the activation and modulation of immune responses in Drosophila.

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Track 12 : Glycomics Business Trends:

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ConferenceSeries Ltd invites all the participants across the globe to attend the International Conference on Glycomics during December 1-2, 2016, Atlanta, USA. Glycomics is closely related to molecular biology, the study of the molecular mechanisms by which genetic information encoded in DNA is able to result in the processes of life. Glycomics-2016 provides a platform where you can meet top notch experts in the field and molecular biologists to discuss molecular mechanisms by which genetic information encoded in DNA.

Glycomics is an emerging medical discipline that involves using genomic information about an individual as part of their clinical care (e.g., for diagnostic or therapeutic decision-making) and the health outcomes and policy implications of that clinical use.

Our Conference will provide a perfect platform addressing:

· Innovative talks by the experts of the global scientific community

· Sterling workshop sessions

· Remarkable Awards and Global Recognition to meritorious Researchers

· Global Networking with 50+ Countries

· Novel Techniques to Benefit Your Research

· Global Business and Networking Opportunities

· Exquisite Platform for showcasing your products and International Sponsorship

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Conference Date	December 08-09, 2016
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Global Congress on Biochemistry, Glycomics and Amino Acids December 08-09, 2016 San Antonio, TX, USA

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