Call For Abstracts | Glycomics 2016 | Biochemistry Conferences | USA | Worldwide Events | Europe | Canada | UK | 2016

Call for Abstract

Scientific Program

Global Congress on Biochemistry, Glycomics and Amino Acids, will be organized around the theme “To evaluate the entire complement of sugars in an Organism”

Biochem Congress 2016 is comprised of 14 tracks and 65 sessions designed to offer comprehensive sessions that address current issues in Biochem Congress 2016.

Submit your abstract to any of the mentioned tracks. All related abstracts are accepted.

Track 1:Glycoproteomics

Comprehensive characterization of protein glycosylation is critical for understanding the structure and function of glycoproteins. However, due to the complexity and heterogeneity of glycoprotein conformations, current glycoprotein analyses focus mainly on either the de-glycosylated glycosylation site (glycosite)-containing peptides or the released glycans. Here, we describe a chemo enzymatic method called solid phase extraction of N-linkedglycans and glycoside-containing peptides (NGAG) for the comprehensive characterization of glycoproteins that is able to determine glycan heterogeneity for individual glycosides in addition to providing information about the total N-linked glycan, glycoside-containing peptide and glycoprotein content of complex samples

Relevant Conferences

International Conference on Structural Biology, June 23-24, 2016 New Orleans, USA; World Congress on Amino Acids and Proteins, December 08-09, 2016 Baltimore, USA; 6^th International Conference on Bioinformatics, March 29-30, 2016 Valencia, Spain; International Conference on Nucleic Acids, August 04-06, 2016 Seattle, USA; 7^th International Conference on Proteomics, October 24-26, 2016 Rome, Italy; International Conference on Obesity & Chronic Diseases, July 25-27, 2016 Las Vegas USA; International Conference on New Therapeutics for Diabetes and Obesity, April 17-20, 2016 La Jolla, USA; Conference on Plasma Spectrochemistry, January 10-16, 2016 Tucson, USA; Euro Fed Lipid Congress, September 18-21, 2016 Gent, Belgium; Society for Glycobiology, 2016; International Obesity and Adipose Tissue Biology Conference, February 15-19, 2016 Banff, Canada

Track 1-1Glycan and Glycan Binding Proteins
Track 1-2Protein-polysaccharide interactions
Track 1-3Peptidoglycan recognition
Track 1-4N-linked Glycoprotein Glycan Analysis and Recognition by GBP
Track 1-5Protein O-glycosylation analysis

Track 2:Clinical Glycomics

Glycomics mainly refers in particular to the enzymatic process that attaches glycans to proteins, lipids, or other organic molecules. This enzymatic process produces one of the fundamental biopolymers found in cells (along with DNA, RNA, and proteins). Glycosylation also plays a role in cell-cell adhesion (a mechanism employed by cells of the immune system) via sugar-binding proteins called lectins, which recognize specific carbohydrate moieties.

Nucleic acids, proteins, lipids, and glycans are the four classes of biomolecules that define life. Recent advances in life science research have painted a very different point of view of the importance of these quintessential biomolecules. Even though our knowledge is still limited, glycans are becoming more important to other fields such as vaccines, therapeutics, diagnostics, materials, and energy. This will subsequently speed up the advancement in other fields, such as research on carbohydrate-based vaccines that require access to well-defined carbohydrate structures and tools.

Relevant Conferences

Track 2-1Genomics Healthcare
Track 2-2Clinical gene therapy
Track 2-3Glycomics Healthcare
Track 2-4Techniques and tools used in clinical genetics

Track 3:Glycomic Analysis

Glycomic analysis increases the diversity of the proteome to a level unmatched by any other post-translational modification. Glycosidases catalyze the hydrolysis of glycosidic bonds to remove sugars from proteins. These enzymes are critical for glycan processing in the ER and Golgi, and each enzyme shows specificity for removing a particular sugar (e.g., mannosidase). Both membrane proteins and the ECM are highly glycosylated, and O-glycans are essential for proper ECM function and communication between cells and the ECM. Several Glycoepitomics forms of CMD are known to result from dysfunctional O-glycosylation of membrane and ECM proteins; however, one-third of CMDs arise from an unknown genetic etiology.

Relevant Conferences

Track 3-1Gene synthesis and its applications
Track 3-2Glycan techniques
Track 3-3Glycans in neuroscience
Track 3-4Gene expression Pattern
Track 3-5O-glycan Analysis and Recognition by GBP

Track 4:Glycomic immunotherapies

Nature appears to have taken full advantage of the vast diversity of glycans expressed in organisms by evolving protein modules to recognize discrete glycans that mediate specific physiological or pathological processes. Excluding glycan-specific antibodies, GBPs broadly into two major groups such as lectins and glycosaminoglycan-binding proteins. Most lectins are members of families with defined “carbohydrate-recognition domains” (CRDs) that apparently evolved from shared ancestral genes, often retaining specific features of primary amino acid sequence or three-dimensional structure. Thus, new family members can be identified by searching protein sequence or structural databases.

Relevant Conferences

Track 4-1The Impact of Genomic Variation in Clinical Development
Track 4-2Application and related disorders
Track 4-3Translational Diagnostics
Track 4-4Tools and technologies for single cell analysis

Track 5:NGS & Data Analysis Technologies

Growth of the mesh-like peptidoglycan (PG) sacculus located between the bacterial inner and outer membranes (OM) is tightly regulated to ensure cellular integrity, maintain cell shape, and orchestrate division. Cytoskeletal elements direct placement and activity of PG synthases from inside the cell, but precise spatiotemporal control over this process is poorly understood. Glycan catabolism contains metabolic pathway maps for glycans. Some of them contain an alternative representation of glycan biosynthesis or degradation, called the glycan structure map. In mammals, complex N-glycans are involved in different cellular processes including molecular recognition and signaling events.

Relevant Conferences

Track 5-1Developments in NGS analysis technologies
Track 5-2Novel techniques and its implementation
Track 5-3Integration of technologies and data sets
Track 5-4Clinical Applications of NGS
Track 5-5Sequencing Technologies

Track 6:Developmental Biology

The recent development of new tools and techniques to study and produce structurally defined carbohydrates has spurred renewed interest in the therapeutic applications of glycans. Essentials of glycobiology review focuses on advances within the past decade that are bringing glycan-based treatments back to the forefront of medicine and the technologies that are driving these efforts. These include the use of glycans themselves as therapeutic molecules as well as engineering protein and cell surface glycans to suit clinical applications to that of databases providing glycoenzyme data. Glycan therapeutics offer a rich and promising frontier for developments in the academic, biopharmaceutical, and medical fields.

Relevant Conferences

Track 6-1Mechanisms of evolutionary changes
Track 6-2Growth factors and oncogenes
Track 6-3Cellular and Molecular Bio-Engineering
Track 6-4Integration of technologies and data sets

Track 7:Microbial & Human Genetics

However, the general development in this field can still be considered as being in its infancy when compared to the genomics and proteomics areas. In terms of bioinformatics in glycobiology, there are several paths of research that are currently in progress. Several algorithms and models have been developed for glycobiology research in the past several years. The development and use of informatics tools and databases for glycobiology and glycomics research has increased considerably in recent years. The development of algorithms and software tools for interpretation of glycans to reliably support the characterization of glycan structures for high-throughput applications is the most immediate demand of the glycomics community.

Relevant Conferences

Track 7-1Emerging and re-emerging infectious disease vaccines
Track 7-2Biodefense Vaccine
Track 7-3Genomics and proteomics of microorganisms
Track 7-4Biomarker tools in microbial diagnosis
Track 7-5Diagnosis and Detection of Viral infections

Track 8:Neurodegenerative Diseases

Carbohydrates form a diverse group of biomolecules which play active parts in most physiological processes. The field of structural glycobiology concerns the structures of the glycans themselves, the proteins which interact with them and the nature of the interactions between the two. Drug targeting is important for our understanding of human health and disease, and for development of new therapeutic strategies. The experts at the Complex Carbohydrate Research Center have experience and knowledge that make us a world leader in this field, and are creating technologies and tools that are the foundation for the next generation of diagnostics and treatments.

Relevant Conferences

Track 8-1Novel drug for neurodegenerative disease
Track 8-2Therapeutic targets for neurodegenerative diseases
Track 8-3Metabolism in neurodegenerative disease
Track 8-4Chemistry of oxidative stress in neurodegenerative disease

Track 9:Glycomics Pathway Analysis

Relevant Conferences

Track 9-1Signalling Pathways in Glycomics
Track 9-2Integrative Biology Analysis
Track 9-3Transcriptomics and Proteomics
Track 9-4High-Throughput Analytical Tools
Track 9-5Glycomics in Membrane protein research

Track 10:Molecular Genetics & Genomics

Molecular Genetics is a field within biology aimed at understanding biological processes and emerging from dynamic interactions of individual components operating at multiple spatiotemporal scales. It is now an established and fundamental interdisciplinary research field. Systems biology studies biological systems by systematically perturbing them (biologically, genetically, or chemically); monitoring the gene, protein, and informational pathway responses; integrating these data; ultimately, formulating mathematical models that describe the structure of the system and predict its response to individual perturbations. Declines in the cost of generating genomic data have made DNA sequencing, RNA-seq, and high-throughput screening an increasingly important part of biomedical research.

Relevant Conferences

Track 10-1Molecular genetics of common and complex diseases
Track 10-2Endoenzymes and its uses
Track 10-3Gene expression & regulation
Track 10-4Tissue Engineering
Track 10-5Genomics of the human glycome

Track 11:Glycomic Diseases

Innate immunity is the front line of self-defense against infectious non-self in vertebrates and invertebrates. The innate immune system is mediated by germ-line encoding pattern recognition molecules (pathogen sensors) that recognize conserved molecular patterns present in the pathogens but absent in the host. Peptidoglycans (PGN) are essential cell wall components of almost all bacteria, except mycoplasma lacking a cell wall, which provides the host immune system an advantage for detecting invading bacteria. Several families of pattern recognition molecules that detect PGN and PGN-derived compounds have been identified, and the role of PGRP family members in host defense is relatively well-characterized in Drosophila. This review focuses on the role of PGRP family members in the recognition of invading bacteria and the activation and modulation of immune responses in Drosophila.

Relevant Conferences

Track 11-1Hypoglycemia
Track 11-2Ketosis & Acidosis
Track 11-3Bacterial glycomics
Track 11-4Glycosuria
Track 11-5Cancer Glycomics

Track 12:Glycogen and Obesity

Glycogen depletion can be forestalled in three possible ways. First, during exercise, carbohydrates with the highest possible rate of conversion to blood glucose are ingested continuously. The best possible outcome of this strategy replaces about 35% of glucose consumed at heart rates above about 80% of maximum. Second, through endurance training adaptations and specialized regimens the body can condition type I muscle fibers to improve both fuel use efficiency and workload capacity to increase the percentage of fatty acids used as fuel, sparing carbohydrate use from all sources. Third, by consuming large quantities of carbohydrates after depleting glycogen stores as a result of exercise or diet, the body can increase storage capacity of intramuscular glycogen stores. Obesity increases the risk of many physical and mental conditions. At an individual level, a combination of excessive food energy intake and a lack of physical activity are thought to explain most cases of obesity. A limited number of cases are due primarily to genetics, medical reasons, or psychiatric illness

Relevant Conferences

Track 12-1Obesity and heart failure
Track 12-2Obesity & cardiovascular outcomes
Track 12-3Cardiorespiratory fitness
Track 12-4Pathogenesis of obesity-related chronic liver diseases
Track 12-5Adipose tissue inflammation and insulin resistance
Track 12-6Obesity glycogenolysis
Track 12-7The microbiome and obesity

Track 13:Glycomics and Diabetes

Diabetes is a major, life-threatening worldwide disease wherein pathological complications include increased risk of infection and cardiovascular disease. The hallmark of diabetic disease is elevated plasma glucose. Within the immune system and vasculature, host-pathogen and regulatory host-host interactions can operate through binding of microbial or host oligosaccharides by proteins of the C-type lectin family. A number of these proteins recognize oligosaccharides rich in mannose and fructose monosaccharide units with similar chemical structures to glucose. This raises the possibility that the high glucose conditions in diabetes affect immunological protein-oligosaccharide interactions via competitive inhibition.

Relevant Conferences

Track 13-1Functional glycomics in diabetes
Track 13-2Glyco-biomarkers for diabetes
Track 13-3Glycosuria

Track 14:Glycomics: Business Trends

Relevant Conferences

Track 14-1Industrial Production of Carbohydrates
Track 14-2Artificial sweeteners - Market value
Track 14-3Global market of Carbohydrate products
Track 14-4Glycomics Growth by 2025

Global Congress on Biochemistry, Glycomics and Amino Acids December 08-09, 2016 San Antonio, TX, USA

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