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International Conference on Glycomics and Proteomics, will be organized around the theme “Advancing & Expanding Glycomics Sector Focused on Developmental Scientific Research”
Glycomics 2021 is comprised of 21 tracks and 0 sessions designed to offer comprehensive sessions that address current issues in Glycomics 2021.
Submit your abstract to any of the mentioned tracks. All related abstracts are accepted.
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Glycan-based biomarkers are currently used for diagnosis of diabetes, cancers, and other complex diseases. We will recapitulate the discovery of glucose, glycated proteins, glycan-, and glycoprotein-based biomarkers followed by summarizing clinically used glycan/glycoprotein-based biomarkers.
Cardiovascular Diseases such as angina and Heart attack which are known as Coronary artery diseases are diagnosed by Proteomics by fulfilling its potential. And many Proteomic techniques are rapidly evolving. The interplay between proteome change and cardiovascular disease can be understood by Biochemical and Physiological methods. Morbidity and Mortality are caused mainly due to Cardiovascular disease which causes deaths. Transcriptome and RNA Profiling is used to outline CVD processes and search for Biomarkers of the disease. DIGE of Rat Heart Proteins Anti-Hypertensive Therapy 2D PAGE for Cardiovascular Proteomics Analyse Cardiac Muscle Proteome.
Pharmacogenomics is the study of how genes affect a person’s response to drugs. This relatively new field combines pharmacology (the science of drugs) and genomics (the study of genes and their functions) to develop effective, safe medications and doses that will be tailored to a person’s genetic makeup. Drug discovery technologies Predictive Prescribing Random Library Screening Limitations of Pharmacogenomics.
Quantitative Proteomics is a Scientific Technique which is used to resolve the amount of protein present in a sample which can be further used to compare between diseased and Healthy patients. It also affords information about differences between samples. Through Mass Spectrometry Isotopic labelling of Proteins or Peptides can be Differentiated. The quantitative Proteomic approach is accordant with the increasingly broad-scope analyses which are used in other life science fields such as genomics, kinemics, transcriptomics, and metabolomics. 2DE-DIGE Mass Spectroscopy Quantitative Dot Blot(QDB) Electrospray Ionization Optimizing LC-Ms/MS for Quantitative Proteomics.
Mass determination and Characterization of proteins can be done through Mass Spectrometry. For Ionization of protein in Mass Spectrometry two methods are used such as Electrospray Ionization and matrix-assisted laser desorption/Ionization. Top-down and Bottom-up approaches are used for the analysis of protein. Tandem Mass Spectrometry Targeted Mass Spectrometry Plasma Mass Spectrometry Gas Source Spectrometry Accelerator Spectrometry.
Applications of proteomics in the discovery of new diagnostic, prognostic and therapeutic targets cover a wide range of example applications for the most important diseases, such as heart and cardiovascular disorders, cancer, pharm toxicology, infectious diseases and diseases of the nervous system. Unraveling Biological Pathways and the Identification of Clinical Markers Clinical proteomics: early diagnosis Technologies for micro proteomic analysis.
Applications of proteomics in the discovery of new diagnostic, prognostic and therapeutic targets cover a wide range of example applications for the most important diseases, such as heart and cardiovascular disorders, cancer, pharm toxicology, infectious diseases and diseases of the nervous system. Unraveling Biological Pathways and the Identification of Clinical Markers Clinical proteomics: early diagnosis Technologies for micro proteomic analysis.
Glycomics is a subset of the field of glycobiology that aims to identify the structure and function of the complete set of glycans produced in a given cell or organism and identify all the genes that encode glycoproteins.
Proteomics refers to the study of proteomes, but is also used to describe the techniques used to determine the entire set of proteins of an organism or system, such as protein purification and mass spectrometry.
Polysaccharide side chains of https://glycomics.conferenceseries.com/proteoglycans or free complex polysaccharides composed of linear disaccharide repeating units each composed of a hexosamine and a hexose or a hexuronic acid. See Heparin, Heparan sulfate, Chondroitin sulfate, Dermatan sulfate, and Hyaluronan.
Glycoproteomic studying uncovers new clinical glycoprotein biomarkers, which can be used for both disease diagnosis and monitoring and evaluating therapeutic efficiency, and even for personal medicine purpose.
Mass spectrometry (MS) based glycomics techniques are broadly used to analyze free oliogsaccharides, glycosaminoglycans as well as the glycan portions of glycoproteins, proteoglycans and glycolipids. A wide range of MS equipment are available for glycoconjugate analysis.
The integration of genomic and proteomic data will help to elucidate the functions of proteins in the pathogenesis of diseases and the ageing process, and could lead to the discovery of novel drug target proteins and biomarkers of diseases.
Clinical glycomics comprises a spectrum of different analytical methodologies to analyze glycan structures, which provides insights into the mechanisms of glycosylation. Within clinical diagnostics, glycomics serves as a functional readout of genetic variants, and can form a basis for therapy development, as was described for PGM1-CDG
A novel approach combining genome-wide association and high-throughput Glycomics analysis of 2,705 individuals in three population cohorts showed that common variants in the Hepatocyte Nuclear Factor 1α (HNF1α) and fucosyltransferase genes FUT6 and FUT8 influence N-glycan levels in human plasma.
An alternative definition is the entirety of carbohydrates in a cell. The glycome may in fact be one of the most complex entities in nature. "Glycomics, analogous to genomics and proteomics, is the systematic study of all glycan structures of a given cell type or organism" and is a subset of glycobiology
Glycoproteins participate in various biological processes, but glycoproteins analysis is a big challenge because of the low abundance and heterogeneity of glycans. Creative Biolabs has successfully explored a series of innovative glycomic profiling platforms to help our clients identify an entire set of N- and O-glycans with high sensitivity and specificity in the biological material.
Glycans in relation to cancer development towards developing clinically useful biomarkers for the early detection of cancer by using a variety of approaches and technologies.
Glycoscience comprises a broad range of knowledge and research on simple and complex carbohydrate metabolism, anabolism, structure, and function. Glycans are expressed in all microorganisms, including prions, as well as in all higher organisms, thus it is not surprising that their biological and disease impacts are profound.
The role of nucleic acid and protein variation in human disease, including HIV, the impact of glycosylation changes has been poorly defined. Glycans decorate nearly all proteins in the body, respond rapidly and dramatically to inflammatory cues, and have been centrally implicated in regulating the immune response
Proteomics technologies have produced a profusion of drug targets, which is creating a lock in drug development process. There is an increasing need for better target recognition for new drug development and proteomic technologies which are contributing to it. Identifying a potential protein Mass spectrometry plays a vital role in proteomics and has become an indispensable tool for molecular and cellular biology.